Introduction Starting in August 2019, the Advanced Imaging Center (AIC) introduced its first pre-commercial electron microscope. This...

What you should know about handling big data Written by Teng-Leong Chew and Eric Wait The era of “big data” in imaging With the recent...

Written by Teng-Leong Chew Photophysics of photobleaching A molecule will emit fluorescent light when its electron, falling from the...

Written by Jesse Aaron Introduction In a previous blog post, we discussed probe selection for single molecule localization microscopy...

Written by Meghan Seltzer Congratulations! Your proposal has just been accepted by the AIC. Your team and the AIC are busy preparing for...

Written by Jesse Aaron Background The last 10 years has seen an explosion of techniques aimed at creating biological fluorescence images...

Written by John Heddleston How is orientation of the Lattice Light Sheet Microscope objectives different? As mentioned in an earlier...

Written by Lin Shao Structured-Illumination Microscopy: What types of sample are not suitable and why Needless to say that, just like in...

Written by Teng-Leong Chew One of the most common questions we receive at the AIC is: what exactly constitutes a strong proposal – what...

Written by John Heddleston The lattice light sheet microscope (LLSM) is a powerful optical tool for observing rapidly-occurring processes...

Written by Teng-Leong Chew The inherent tendency of fluorescent molecules to photobleach has been turned into a very powerful tool for...

Written by Jesse Aaron For many researchers, the prospects afforded by super-resolution (SR) imaging are both vast and exciting. The...